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| First Round Draft Pick History |
| 1 | 7 | 7 | 2022 | Annual Draft | P | Chris | Flexen | MLB |
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| 1 | 10 | 10 | 2021 | Annual Draft | 2B | Nick | Madrigal | MLB |
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| Complete Draft History |
| 1 | 7 | 7 | 2022 | Annual Draft | P | Chris | Flexen | MLB |
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| 2 | 6 | 26 | 2022 | Annual Draft | 1B | Frank | Schwindel | MLB |
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| 3 | 7 | 47 | 2022 | Annual Draft | P | Bailey | Ober | MLB |
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| 4 | 6 | 66 | 2022 | Annual Draft | P | Keegan | Thompson | MLB |
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| 5 | 7 | 87 | 2022 | Annual Draft | P | Sam | Coonrod | MLB |
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| 6 | 6 | 106 | 2022 | Annual Draft | P | Tylor | Megill | MLB |
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| 7 | 7 | 127 | 2022 | Annual Draft | P | Hirokazu | Sawamura | MLB |
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| 8 | 6 | 146 | 2022 | Annual Draft | P | Juan | Minaya | MLB |
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| 11 | 7 | 207 | 2022 | Annual Draft | P | Tyler | Kinley | MLB |
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| 12 | 6 | 226 | 2022 | Annual Draft | OF | Luke | Williams | MLB |
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| 1 | 10 | 10 | 2021 | Annual Draft | 2B | Nick | Madrigal | MLB |
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| 2 | 10 | 30 | 2021 | Annual Draft | P | Tanner | Houck | MLB |
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| 3 | 10 | 50 | 2021 | Annual Draft | 1B | Josh | Fuentes | MLB |
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| 4 | 10 | 70 | 2021 | Annual Draft | P | Cody | Ponce | MLB |
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| 5 | 10 | 90 | 2021 | Annual Draft | P | Pete | Fairbanks | MLB |
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| 6 | 10 | 110 | 2021 | Annual Draft | P | Trevor | Cahill | MLB |
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| 7 | 10 | 130 | 2021 | Annual Draft | P | Tyler | Matzek | MLB |
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| 8 | 10 | 150 | 2021 | Annual Draft | P | Geoff | Hartlieb | MLB |
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| 9 | 10 | 170 | 2021 | Annual Draft | P | Tyler | Alexander | MLB |
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| 10 | 10 | 190 | 2021 | Annual Draft | P | Aaron | Slegers | MLB |
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| 11 | 10 | 210 | 2021 | Annual Draft | P | Jimmy | Herget | MLB |
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| 12 | 10 | 230 | 2021 | Annual Draft | OF | Taylor | Ward | MLB |
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